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Over the millennia, the often deified and sometimes demonized Cannabis
plant has taken a circuitous route from friend to foe and back.
Scholars differ on when mankind first discovered the medicinal mysteries
contained within Cannabis. Some trace usage back to 4000 BC in Central
Asia. Charred seeds found in an ancient Romanian burial site suggest
inhalation of the herb's potent and pungent smoke in third millennia BC.
In 1500 BC, it was mentioned the Altharva Veda, one of four ancient holy
books. A basket of seeds and leaf fragments dating back 2,800 years was
discovered in China where Cannabis graced the pharmacopeia of emperor
Chen-Nong. As if following the migrational footsteps of humanity, the
plant moved to the Near and Middle East (900 BC), Europe (800 BC), South
East Asia (2nd Century AD), Africa (11th Century AD) and finally to the
Americas (19th Century).
In 1839, William O'Shaughnessy introduced Cannabis to Western medicine
with a 40-page paper entitled, "On the Prescription of Indian Hemp or
Ganga." Shortly thereafter, its medicinal properties were documented in
the "Report of the Ohio State Medical Committee on Cannabis Indica,"
which was written by influential physicians and presented in 1860 at the
Fifteenth Annual Meeting of the Ohio State Medical Society. This report
extoled "beneficial effects" of Cannabis on tetanus, neuralgia,
insomnia, labor, convulsions, seizures, rheumatism, pain relief and a
host of other ailments. For the next 75 years, the U.S. Pharmacopeia
listed Cannabis as an effective treatment for these and many other
conditions.
But the pendulum swung the other way. The 75 years that followed
produced increasingly draconian restrictions. Cannabis entered its Dark
Ages. It became caught in the prohibitionist and racists moods that
tainted much of the 20th century, culminating in its removal from the
U.S. Pharmacopeia in 1942. Steep penalties and sanctions suppressed its
use. New drugs were developed to take its place, and those who dared do
as their ancestors had done were slapped with mandatory minimum
sentences and bank account-breaking fines.
Then, one visionary man planted the seeds of a momentous counter swing.
In 1964, Dr. Raphael Mechoulam, Professor of Medicinal Chemistry at the
Hebrew University of Jerusalem, identified the chemical components of
cannabis - cannabinoids - by first synthesizing THC
(delta-9-tetrahydrocannabinol) and then discovering the chemical
structure of its cousin, CBD (cannabidiol).
The good doctor was also instrumental in another amazing discovery:
cannabinoids exist in each and every one of us. In 1992, he and his team
identified the endogenous cannabinoid that he named anandamide, Sanskrit
for "eternal bliss," apropos because of its control over emotions,
memory and movement. Around the same time, "receptors" in the brain and
elsewhere the body were found to bond specifically with this internal
cannabinoid, as well as with plant-based and lab synthesized ones. Upon
discovery of the endogenous endocannabinoid system, the direct tie to
cannabis' medicinal properties had been established.
Research accelerated. A search of PubMed.gov, the library of clinical
research, would only have found 200 or so studies pertaining to
cannabinoids in the 1970s; a search today located 17,056.
The cannabinoid receiving much of this interest has been CBD. Unlike its
cannabinoid cousin, THC, CBD does not create a "high," unless simply
feeling better counts. Consider these findings:
Cancer. "In conclusion, a cannabinoid-based therapeutic strategy for
neural diseases devoid of undesired psychotropic side effects could find
in CBD a valuable compound in cancer therapies." _Pharmacological
Reviews_.
Diabetic Cardiomyopathy. "Collectively, these results coupled with the
excellent safety and tolerability profile of CBD in humans, strongly
suggest that it may have great therapeutic potential in the treatment of
diabetic complications, and perhaps other cardiovascular disorders, by
attenuating oxidative/nitrative stress, inflammation, cell death and
fibrosis." _Journal of the American College of Cardiology_.
Substance abuse treatment. "Clearly, greater attention needs be given to
the potential role of CBD in the treatment of addiction and other mental
health disorders." _The Journal of Neuroscience_.
Do these studies have an Ohio State Medical Society ring to them? Was it
the action of CBD that was described to the Society in 1860? Inspired by
CBD and influenced by Dr. Meschoulam's work, the famed Dr. Sanjay Gupta
recently changed his view toward marijuana, vowing to reverse its Dark
Ages course.
Cannabis' circuitous journey into the 21st Century has been
transformative. The once demonized plant is now viewed as not only
useful and therapeutic, but also fundamental to human physiology.
Cannabis is more than just a high. Its many components, particularly
CBD, may embody the remedies described in ancient books, centuries-old
annals and current medical journals. Because an endogenous bodily system
bonds directly to them, CBD and the other cannabinoids aren't just mere
chemicals; they form a core part of you … and of me.
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Addendum: The amazing benefits of cannabidiol (CBD)-rich hemp with no
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HempmedsPx is a corporate sponsor of the Ohio Rights Group and Cheryl
Shuman, who recently toured the state in support of the Ohio Cannabis
Rights Amendment. For more information on HempmedsPx, please visit
http://hempmedspx.com/index.php/order-products . Information on the
Ohio Rights Group and the Ohio Cannabis Rights Amendment can be found at
http://www.ohiorightsgroup.org/ .